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...Study
In 2005, University of California–Berkeley researchers made the surprising discovery that when young and old mice share blood and organs, rejuvenated tissues can reverse the signs of aging in the old mice. The finding sparked a flurry of research into whether a youngster’s blood might contain special proteins or molecules that could serve as a sort of “fountain of youth” for mice and humans alike.
But a new study by the same team shows that similar age-reversing effects can be achieved by simply diluting the blood plasma of old mice—no young blood needed.
In the study, the team found that replacing half of the blood plasma of old mice with a mixture of saline and albumin—where the albumin simply replaces protein that was lost when the original blood plasma was removed—has the same or stronger rejuvenation effects on the brain, liver and muscle than pairing with young mice or young blood exchange. Performing the same procedure on young mice had no detrimental effects on their health.
This discovery shifts the dominant model of rejuvenation away from young blood and toward the benefits of removing age-elevated, and potentially harmful, factors in old blood.
Continued below.
Diluting Plasma Shown to Rejuvenate Tissue and Reverse Signs of Aging in Old Mice, Says Cool New Study
In 2005, University of California–Berkeley researchers made the surprising discovery that when young and old mice share blood and organs, rejuvenated tissues can reverse the signs of aging in the old mice. The finding sparked a flurry of research into whether a youngster’s blood might contain special proteins or molecules that could serve as a sort of “fountain of youth” for mice and humans alike.
But a new study by the same team shows that similar age-reversing effects can be achieved by simply diluting the blood plasma of old mice—no young blood needed.
In the study, the team found that replacing half of the blood plasma of old mice with a mixture of saline and albumin—where the albumin simply replaces protein that was lost when the original blood plasma was removed—has the same or stronger rejuvenation effects on the brain, liver and muscle than pairing with young mice or young blood exchange. Performing the same procedure on young mice had no detrimental effects on their health.
This discovery shifts the dominant model of rejuvenation away from young blood and toward the benefits of removing age-elevated, and potentially harmful, factors in old blood.
Continued below.
Diluting Plasma Shown to Rejuvenate Tissue and Reverse Signs of Aging in Old Mice, Says Cool New Study
